Ngenla® (somatrogon-ghla)

What is Ngenla?

Ngenla is a prescription growth hormone medicine. It is used to treat children who do not make enough natural growth hormone.

Ngenla is a long-acting growth hormone medicine. It is given once a week instead of every day.

What is growth hormone?

Growth hormone is made by the pituitary gland, a small gland in the brain. It helps children:

• Grow taller
• Build muscles
• Strengthen bones
• Maintain healthy energy levels

Some children do not make enough growth hormone. This is called growth hormone deficiency.

Children with growth hormone deficiency may:

• Grow more slowly than other children
• Be shorter than expected for their age
• Have lower energy
• Gain extra body fat

How is Ngenla given?

Ngenla is:

• Given as a shot under the skin
• Usually given once every week
• Given on the same day each week

Common injection sites include:

• Stomach
• Thighs
• Upper arms
• Buttocks

It is important to rotate injection sites to help prevent skin irritation.

Your child’s healthcare team will teach you how to safely give the injections.

How should Ngenla be stored?

• Keep Ngenla in the refrigerator
• Do not freeze it
• Protect it from direct light
• Keep out of reach of children

Always follow the storage instructions from your pharmacy and healthcare provider.

What are common side effects?

Many children do well on Ngenla. Common side effects may include:

• Redness or pain where the shot was given
• Headache
• Muscle or joint pain
• Swelling of hands or feet
• Tiredness
• Mild stomach pain

These side effects are usually mild.

When should I call the doctor?

Call your child’s healthcare provider if your child has:

• Severe headaches
• Vision changes
• Hip or knee pain
• Limping
• Severe swelling
• Trouble breathing
• Severe stomach pain
• Signs of high blood sugar, such as increased thirst or urination
• Signs of an allergic reaction such as rash, swelling, or trouble breathing

Get emergency medical help right away for severe allergic reactions or breathing problems.

Important safety information

Tell your child’s healthcare provider if your child has:

• Diabetes
• Scoliosis
• Sleep apnea
• A history of cancer
• Recent surgery or serious illness

Your child will need regular clinic visits and lab work while taking Ngenla.

Tips for families

• Give the medicine on the same day each week
• Use reminders or calendars to track doses
• Rotate injection sites
• Keep follow-up appointments
• Monitor your child’s growth over time

Growth hormone treatment often lasts for several years.

Questions?

If you have questions about Ngenla, contact your pediatric endocrinology team at Endo For Kids.